Chiral allene-containing phosphines in asymmetric catalysis.
نویسندگان
چکیده
We demonstrate that allenes, chiral 1,2-dienes, appended with basic functionality can serve as ligands for transition metals. We describe an allene-containing bisphosphine that, when coordinated to Rh(I), promotes the asymmetric addition of arylboronic acids to α-keto esters with high enantioselectivity. Solution and solid-state structural analysis reveals that one olefin of the allene can coordinate to transition metals, generating bi- and tridentate ligands.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 133 45 شماره
صفحات -
تاریخ انتشار 2011